The family of US actress Anne Heche says she is not expected to survive, after a car crash earlier this week that left her vehicle engulfed in flames.
She remains in a coma and had “a severe anoxic brain injury” – when the brain is deprived of oxygen – they said.
“We want to thank everyone for their kind wishes and prayers for Anne’s recovery and thank the dedicated staff and wonderful nurses,” they added.
Her car crashed into a two-storey home in Los Angeles last week.
Police said on Friday that preliminary blood tests had revealed the presence of drugs in her system, but extra testing was needed to rule out any substances given in hospital.
The Los Angeles Police Department told the PA news agency the incident was being investigated as a felony driving-under-the-influence traffic collision.
Her other film credits include I Know What You Did Last Summer, Prozac Nation, Volcano and Six Days, Seven Nights – which saw her star opposite Harrison Ford.
She was nominated for outstanding younger actress in a drama series at the Daytime Emmy Awards in 1991, for her performance in Another World.
Her other TV work includes appearances in Ally McBeal, Save Me, Aftermath, Hung, Chicago P.D. and Men in Trees.
Heche has also appeared on Dancing with the Stars, the US equivalent of Strictly Come Dancing.